Молекулярний аналіз тонких плівок різної природи на основі спектроскопії поверхневих плазмонів
DOI:
https://doi.org/10.35681/1560-9189.2018.20.4.178531Ключові слова:
поверхневий плазмонний резонанс, тонкі плівки, халькогенідний склоподібний напівпровідник, поліанілін, фібриноген, моно-клональні антитілаАнотація
Досліджено процеси формування та структуру тонких плівок халькогенідного склоподібного напівпровідника As2S3, полімеру поліаніліну (ПАНІ) та білка фібриногену (ФБ) на поверхні плівок благородних металів (Ag, Au) з використанням методики призмового збудження поверхневого плазмонного резонансу (ППР) у поєднанні з атомно-силовою мікроскопією. Оптичні параметри шарів As2S3 та ПАНІ визначено при підганянні експериментальних і розрахованих резонансних кривих ППР методом мінімізації цільової функції. Властивості плівок ФБ, що отримані з розчину білка у фосфатному буфері при різних концент-раціях (9,3–300 muг/мл), вивчено на основі аналізу кінетичних ППР-кривих адсорбції ФБ і його DD- і E-фрагментів з наступним зондуванням моноклональними антитілами.Посилання
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